I le taimi nei, o le faʻataʻitaʻiga faʻamaneta (MRI) o loʻo atiaʻe mai faʻataʻitaʻiga faʻavae masani ma ata faʻatino i ata mole. Multi-nuclear MR E mafai ona maua le tele o faʻamatalaga metabolite i totonu o le tino o le tagata, aʻo faʻatumauina le faʻaogaina o avanoa, faʻaleleia le faʻapitoa o le suʻesuʻeina o faiga faʻaletino ma pathological, ma o le taimi nei naʻo le tekinolosi e le mafai ona faʻaogaina le suʻesuʻeina faʻatusatusaga o le tino mole mole metabolism i vivo.
Faʻatasi ai ma le faʻalolotoina o le tele-core MR Research, o loʻo i ai avanoa lautele faʻaogaina i le vave suʻesuʻeina ma suʻesuʻega o tuma, faʻamaʻi cardiovascular, faʻamaʻi neurodegenerative, endocrine system, faʻamaʻi faʻamaʻi ma faʻamaʻi manava, ma iloiloga vave o togafitiga. Ole tulaga fou ole su'esu'ega fa'afoma'i a le Philips ole a fesoasoani ile fa'ata'ita'iga ma foma'i ile fa'atinoina o su'esu'ega fa'afoma'i. Na tuuina mai e Dr. Sun Peng ma Dr. Wang Jiazheng mai le Philips Clinical and Technical Support Department se faʻamatalaga auiliili i le atinaʻeina o le tele-NMR ma le suʻesuʻega o le Philips' fou multi-core MR Platform.
Ua manumalo le Magnetic Resonance i le Nobel Prize i le lima taimi i lona talafaasolopito, i le tele o matata o le fisiki, kemisi, biology, ma vailaau, ma ua ausia le manuia tele i mataupu faavae o le fisiki, fausaga mole mole, biological macromolecular structure dynamics, ma ata faafomai. Faatasi ai ma i latou, o le faʻataʻitaʻiga o le magnetic resonance ua avea ma se tasi o tekinolosi faʻataʻitaʻiga faafomaʻi sili ona taua, faʻaaogaina lautele i le suʻesuʻeina o faʻamaʻi eseese i vaega eseese o le tino o le tagata. Faʻatasi ai ma le faʻaauau pea o le faʻaleleia atili o manaʻoga o le soifua maloloina, o le manaʻoga tele mo suʻesuʻega vave ma le vave suʻesuʻeina o le faʻaleleia o le faʻaleleia o le atinaʻeina o faʻataʻitaʻiga faʻamaneta mai faʻataʻitaʻiga masani (T1w, T2w, PDw, ma isi), faʻataʻitaʻiga galue (DWI, PWI, ma isi) i le molecular imaging (1H MRS Ma multi-core MRS / MRI).
O le fa'alavelave lavelave o le 1H fa'avae MR Tekinolosi, va'aiga fa'apipi'i, ma vai/ga'o fa'apipi'i fa'atapula'aina lona avanoa e avea o se tekonolosi fa'ata mole mole. E naʻo se numera faʻatapulaʻa o molelaʻau (choline, creatine, NAA, ma isi) e mafai ona iloa, ma e faigata ona maua le faʻagasologa o le metabolic molecular. Faʻavae i luga o le tele o nuclides (23Na, 31P, 13C, 129Xe, 17O, 7Li, 19F, 3H, 2H), multi-nuclear MR E mafai ona maua le tele o faʻamatalaga metabolite o le tino o le tagata, faʻatasi ai ma le maualuga maualuga ma le faʻamaonia maualuga, ma o le taimi nei na o le pau lea o le non-invasive, le faʻamaufaʻailogaina o le radioactivity endogen; (glucose, amino acids, fatty acids – non-toxic) mo su'esu'ega fa'afuainumera o fa'agaioiga mole mole ga'o fa'agaioiga a le tagata.
Faʻatasi ai ma le faʻaauauina o faʻalavelave i le faʻaogaina o masini maneta, auala faʻasolosolo vave (Multi-Band, Spiral) ma le faʻavaveina o algorithm (faʻapipiʻiina lagona, aʻoaʻoga loloto), multi-core MR Imaging / spectroscopy e faasolosolo ona matua: (1) e faʻamoemoeina e avea ma meafaigaluega taua mo le faʻaogaina o meaola mole mole, biochemistry ma suʻesuʻega metabolism tagata; (2) A o agaʻi mai suʻesuʻega faʻasaienisi i faʻataʻitaʻiga faʻapitoa (o le tele o faʻataʻitaʻiga faʻapitoa e faʻavae i luga o le tele-core MR Are in progress, FIG. 1), o loʻo i ai le tele o faʻamoemoega i le vave suʻesuʻeina ma suʻesuʻega o le kanesa, cardiovascular, neurodegenerative, digestive and respiratory diseases, ma le vave suʻesuʻeina o le aoga.
Ona o le lavelave o mataupu fa'aletino ma le maualuga o le faigata fa'atekinisi o le MR Field, multi-core MR Sa avea ma vaega fa'apitoa su'esu'ega a nai fa'alapotopotoga su'esu'e fa'ainisinia maualuluga. E ui o le multicore MR Ua matua'i alualu i luma ina ua mavae le tele o tausaga o atina'e, ae o lo'o i ai pea le le lava o fa'amaumauga fa'afoma'i e fa'agasolo ai lenei matā'upu e tautua moni ai ma'i.
Faʻavae i luga o faʻafouga faifai pea i le matata o le MR, na iu ai ina gau e Philips le fagu faʻaleleia o le tele-core MR Ma faʻasalalau se faʻavae suʻesuʻega faʻafomaʻi fou ma le tele o nuclides i le alamanuia. O le fa'avae e na'o le pau lea o le tele-core system i le lalolagi e maua ai le EU Safety Conformity Certification (CE) ma le US Food and Drug Administration (FDA) certification, e mafai ai ona maua se oloa-level multi-core MR Solution: FDA-approved coils, full sequence coverage, and operator station reconstruction standard. E le manaʻomia e tagata faʻaoga le faʻapipiʻiina o fomaʻi faʻapolofesa maneta resonance, inisinia faʻailoga ma RF gradient designers, lea e sili atu le faigofie nai lo le masani 1H spectroscopy / ata. Fa'ateleina le fa'aitiitiga o le tele-core MR tau fa'agaioiga, fesuia'i fua i le va o su'esu'ega fa'asaienisi ma le fa'ata'ita'iga fa'ata'ita'i, o le tau sili ona vave toe fa'aleleia, ina ia mafai ai e le tele-core MR Moni i totonu o le falema'i.
Multi-core MR Ua avea nei ma taʻiala autu o le "14th Five-Year Five-Year Medical Equipment Industry Development Plan", ma o se tekinolosi autu autu mo ata faʻafomaʻi e malepe ai le masani ma tuʻufaʻatasia ma biomedicine pito sili ona lata mai. Philips Saina Saienitisi vaega, fa'aosoina e ala i le fa'aleleia atili o su'esu'ega fa'asaienisi ma agava'a fou a tagata fa'atau, fa'atautaia su'esu'ega fa'apitoa ile tele-core MR. Dr. Sun Peng, Dr. Wang Jiazheng et al. muamua na tuʻuina atu le manatu o le MR-nucleomics i le NMR i Biomedicine (pito i luga Journal of the First Region of Spectroscopy of Chinese Academy of Sciences), lea e mafai ona faʻaogaina le MR Faʻavae i luga o nuclides eseese e mataʻituina ai le tele o gaioiga sela ma faiga pathological. O le mea lea, e mafai ona faia le faʻamasinoga atoatoa ma le iloiloga o faʻamaʻi ma togafitiga [1]. Ole manatu ole MR Multinucleomics ole a avea ma ta'iala ile lumana'i ole MR Development. O lenei pepa o le uluai iloiloga faʻatulagaina o le tele-core MR I le lalolagi, e aofia ai le faʻavae faʻavae o le tele-core MR, suʻesuʻega a le falemaʻi, suʻesuʻega falemaʻi, atinaʻe meafaigaluega, alualu i luma algorithm, faʻainisinia ma isi vaega (Ata 2). I le taimi lava e tasi, na galulue faʻatasi le 'au a saienitisi ma Polofesa Song Bin o le Falemai i Sisifo Saina e faʻamaeʻa le uluaʻi iloiloga tusiga i luga o le suiga o le falemaʻi o le tele-core MR In China, lea na lomia i totonu o le tusi talaaga Insights into Imaging [2]. O le fa'asalalauina o fa'asologa o tala i luga ole multicore MR Fa'aalia o Philips o lo'o aumaia moni lava le tua'oi ole fa'ata'ita'iga mole mole tele i Saina, i tagata fa'atau Saina, ma tagata mai Saina. E tusa ai ma le manatu autu o le "i Saina, mo Saina", Philips o le a faʻaogaina le tele-core MR E faʻalauiloa ai le atinaʻeina o le maneta o Saina ma fesoasoani i le mafuaʻaga o le soifua maloloina o Saina.
O le tele-nuclear MRI o se tekonolosi faʻalauiloa. Faatasi ai ma le atinaʻeina o MR Software ma meafaigaluega, multi-nuclear MRI ua faʻaaogaina i suʻesuʻega faʻaliliuga faʻavae ma falemaʻi o faiga a tagata. O lona tulaga tulaga ese o le mafai lea ona faʻaalia taimi moni faʻagasologa metabolic malosi i faiga pathological eseese, ma maua ai avanoa mo le vave suʻesuʻeina o faʻamaʻi, iloiloga lelei, faia o filifiliga togafitiga ma le atinaʻeina o vailaʻau. E mafai foi ona fesoasoani e suʻesuʻe auala fou o pathogenesis.
Ina ia faʻalauteleina le faʻalauteleina o le atinaʻeina o lenei matata, e manaʻomia le auai malosi o tagata tomai faapitoa ile falemaʻi. O le atinaʻeina o falemaʻi o multicore platforms e taua tele, e aofia ai le fausiaina o faiga faʻavae, le faʻavasegaina o tekinolosi, le faʻatusatusaina ma le faʻavasegaina o taunuʻuga, le suʻesuʻeina o suʻesuʻega fou, le tuʻufaʻatasia o le tele o faʻamatalaga metabolic, ma isi. Matou te matua talitonu o le tele-core MR O le a tuʻuina atu se tulaga lautele mo faʻataʻitaʻiga ma tagata tomai faʻapitoa e faia suʻesuʻega falemaʻi, ma o ona taunuuga o le a manuia ai tagata gasegase i le lalolagi atoa.
Taimi meli: Tes-09-2023